Sowu Supply Pazopanibr Hydrochloride CAS 444731-52-6 Pazopanib

• Customization: Available
• CAS No.: 444731-52-6
• Formula: C21h23n7o2s
• Model NO.: SWP-C031
• EINECS: /
• Type: Pharmaceutical Intermediates
• Appearance: Powder
• Quality: Pharmaceutical Intermediate
• Colour: White
• MW: 437.52
• Mf: C21h23n7o2s
• Grade: Pharmaceutical Grade
• Purity: 99%
• Suitable for: Adult
• State: Powder
• Color: White Powder
• MOQ: 10g
• Test Method: HPLC
• Shelf Life: 2 Years
• Density: 1.40
• Extraction Type: Solvent Extraction
• Sample: Available
• Storage: Cool and Dry Place
• OEM: Accept
• Transport Package: Vacuum Sealed Foil Bag
• Specification: 10g/bag
• Trademark: Sowu
• Origin: China
• Production Capacity: 80kg

Product Description

Product Description

Pazopanib is researched and developed by a GlaxoSmithKline ,it is a novel oral vascular generation inhibitor which may interfere stubborn tumor survival and new blood vessels generation growth needed .Targeting receptor (VEGFR),it works by inhibiting angiogenesis of tumor blood supply.   it is suitable for advanced renal cell carcinoma ( a discovery of cancer cells in the renal tubules), soft tissue sarcoma (STS), epithelial ovarian cancer and non-small cell lung cancer (NSCLC) treatment.

Certifications

    

Product name	Pazopanib	Manufacture date	Jan.14.2025
Batch number	SW250114	Analysis date	Jan.15.2025
Batch quantity	80kg	Expire date	Jan.14.2027

 

Item	Specification	Result
Appearance	White powder	Conforms
Odor	Characteristic	Conforms
Heavy Metal	≤5ppm	0.09ppm
As	≤2ppm	0.07ppm
Pesticides	Negative	Negative
Loss on drying	≤0.5%	0.23%
Total plate count	≤1000cfu/g	Conform
Yeast & mold	≤100cfu/g	Conform
Residue on ingnition	≤1.0%	0.19%
Assay	>99%	99.18%
E.coil	Negative	Negative
Salmonella	Negative	Negative

 

Packing description:	Sealed export grade drum & double of sealed plastic bag
Storage:	Store in cool & dry place not freeze., keep away from strong light and heat
Shelf life:	2 years when properly stored

 

Application

Pazopanib is an oral multi-target tyrosine kinase inhibitor that can block various receptors including VEGFR1-3, PDGFR - α, PDGFR - β, and c-KIT. Its mechanism of action is very similar to sorafenib and sunitinib
Indications for Pazopanib:
FDA approved for use in patients with advanced kidney cancer.
2. FDA approval for advanced soft tissue sarcoma (STS) patients who have previously received chemotherapy. However, the therapeutic effect on fatty STS or gastric stromal tumors has not yet been determined. Trial data for the treatment of soft tissue sarcoma: Phase III clinical trial

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FAQ

1. Customs clearance
1) By Express:
Normally there is no specical need for the recipient to clear the customs. If the customs has an objection,our rich experienced and professional group will help you clear the customs.
2) By Air and by Sea:
Our company will cooperate with the recipient to provide relevant file and information in the customs clearance procedure.
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