Citicoline sodium is an organic substance with the chemical formula C14H25N4NaO11P2, white crystalline powder. It is mainly used for acute head trauma and consciousness disturbance after brain surgery. By reducing cerebral vascular resistance and increasing cerebral blood flow, it promotes brain metabolism and improves cerebral circulation. It can also enhance the function of the brainstem ascending reticular activation system, enhance the function of the vertebral system, and improve motor paralysis, so it has a certain effect on promoting the recovery of brain function and promoting awakening.
| Product name |
Citicoline Sodium |
Manufacture date |
Dec.09.2024 |
| Batch number |
SW241209 |
Analysis date |
Dec.13.2024 |
| Batch quantity |
100kg |
Expiry date |
Dec.09.2026 |
| Item |
Standard |
Results |
| Appearance |
White powder |
Confirms |
| Identification |
1. Chemical reaction |
Positive reaction |
| |
2. The retension time of a major peak meets the requirements |
Confirms |
| |
3. IR: consistent with the spectrum obtained with reference substance |
Confirms |
| |
4. Show sodium flam |
Positive reaction |
| PH |
6.0-7.5 |
6.5 |
| Chlorides |
N.M.T. 0.05% |
Confirms |
| Ammonium |
N.M.T. 0.05% |
Confirms |
| Iron |
N.M.T. 0.01% |
Confirms |
| Phosphate |
N.M.T. 0.1% |
Confirms |
| Related substance |
| 5'-CMP |
N.M.T. 0.3% |
0.019% |
| Other larger impurities |
N.M.T. 0.2% |
0.039% |
| Other impurities total |
N.M.T. 0.7% |
0.039% |
| Residual solvents |
|
| Ethanol |
N.M.T. 0.5% |
Negative |
| Loss on drying |
N.M.T. 6.0% |
1.70% |
| Heavy metals |
N.M.T. 5ppm |
Confirms |
| Arsenic |
N.M.T. 0.0001% |
Confirms |
| Endotoxin |
N.M.T. 0.3 EU/mg |
Confirms |
| Assay |
≥99.0% |
99.88% |
| Packing description: |
Sealed export grade drum & double of sealed plastic bag |
| Storage: |
Store in cool & dry place not freeze., keep away from strong light and heat |
| Shelf life: |
2 years when properly stored |
1.It is mainly used for consciousness disorders after acute head injury and brain surgery.
2. Impairment of consciousness in the acute stage of cerebral infarction.
3. It can be used for ischemic cerebrovascular disease, vascular dementia, tinnitus and neural deafness.
4. It can also be applied to coma and consciousness disorder caused by acute poisoning, infection, and large-scale cerebral infarction.
5. It is helpful for the recovery of upper and lower limb function of patients with sequelae of stroke and hemiplegia after stroke, and can be used together with medications that promote cerebral metabolism and cerebral circulation. However, it is limited to patients with mild hemiplegia in cases of functional rehabilitation training and usual oral medication therapy (cerebral metabolic activators, cerebral circulation medications improvement, etc.) within one year after the onset of the disease.
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