Folic acid, commonly known as folate or Vitamin B9. Other name also has Vitamin M, Vitamin Bc and Antianemia factor. Its chemical structure, pteroylglutamic acid, comprises a pteridine ring, para-aminobenzoic acid, and glutamic acid. Naturally occurring in leafy greens, legumes, and liver, folate plays a vital role in DNA synthesis, red blood cell formation, and amino acid metabolism. Synthetic folic acid is widely used in dietary supplements and fortified foods. Critical for fetal neural development, it prevents birth defects like spina bifida. Adults require it for cardiovascular health and cognitive function. Deficiency causes anemia and fatigue. Daily intake: 400 mcg for adults, 600 mcg for pregnant women.
| Product name |
Folic acid/Vitamin B9 |
Manufacture date |
Feb.22.2025 |
| Batch number |
SW250222 |
Analysis date |
Feb.23.2025 |
| Batch quantity |
500kg |
Expiry date |
Feb.22.2027 |
| Items |
Specifications |
Results |
| Appearance |
Yellow crystalline powder |
Conform |
| Odor |
Characteristic |
Conform |
| Assay |
NLT99% |
99.12% |
| Size |
NLT 95% through 80 mesh |
Conform |
| Loss on Drying |
5.0%Max |
1.26% |
| Residue on Ignition |
NMT 0.1% |
0.03% |
| Residual Ethanol |
NMT 0.5% |
0.32% |
| Heavy Metal |
NMT 5ppm |
Conform |
| Pb |
≤2ppm |
Conform |
| Na |
NMT 0.1% |
0.02% |
| Total Plate count |
≤1000 cfu/g |
Conform |
| Yeast&Mold |
NMT 100cfu/g |
Conform |
| Salmonella |
Negative |
Negative |
| E.Coli |
Negative |
Negative |
| Conclusion |
Conform to specifications |
| Packing description: |
Sealed export grade drum & double of sealed plastic bag |
| Storage: |
Long-term storage is below 15 degrees below zero |
| Shelf life: |
2 years when properly stored |
Folic acid is widely distributed in leafy greens such as spinach, beet, and broccoli, as well as animal-based foods (liver, kidney, egg yolk), fruits (citrus, kiwi), and yeast. However, it is less abundant in root vegetables, corn, rice, and pork. Among leafy greens, the highest folate concentrations are found in specific varieties like Doellingeria scabra (east wind herb), Caltha palustris (marsh marigold), Adenocaulon himalaicum (mountain cress), Artemisia integrifolia (willow herb sprouts), Eleutherococcus senticosus , and wild asparagus.
1. Animal Applications
Swine:
Supplementing 2.5 mg/kg folic acid in piglet diets significantly improves daily weight gain, serum protein levels, and hepatic DNA/RNA/protein content while reducing urea nitrogen. Overdosing (>2.5 mg/kg) may impair growth. In sows, folic acid elevates maternal and neonatal serum folate levels and reduces oxidative stress by lowering homocysteine.
Dairy Cattle:
While rumen microbes synthesize folate, high-yielding dairy cows require dietary supplementation during pregnancy. Folic acid and choline enhance energy/protein metabolism and DNA synthesis, boosting milk production.
Poultry:
Optimal folic acid supplementation (1.64-3.0 mg/kg) improves feed intake, weight gain, and serum protein in broilers. Synergy with niacin further enhances growth, reduces fat deposition, and strengthens immune organ indices (thymus, spleen).
2. Pharmaceutical Applications
Neural Tube Defects (NTDs):
Prenatal folic acid (0.4 mg/day) reduces NTD risk by 85%, as proven by the Sino-US Collaborative Project. Fortified foods in the US lowered NTD births by 19%. Pregnant/lactating women require 400-600 μg daily.
Cardiometabolic Health:
Folate lowers homocysteine, mitigating risks of cardiovascular diseases, dementia, and depression. It also reduces gout incidence and inhibits colorectal neoplasms recurrence.
Oncology:
Folic acid enhances chemotherapy sensitivity in ovarian neoplasms by disrupting folate metabolism in malignant cells.
3. Safety & Guidelines
5 mg/day doses remedy anemia but require medical supervision.
Deficiency correlates with digestive disorders (e.g., gastritis, colon neoplasms).
1. Customs clearance
a. By Express:
Normally there is no specical need for the recipient to clear the customs. If the customs has an objection, our rich experienced and professional group will help you clear the customs.
b. By Air and by Sea:
Our company will cooperate with the recipient to provide relevant file and information in the customs clearance procedure.
2. Payment
L/C, T/T, D/P, Western Union, Paypal, Money Gram, USDT, etc.
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