Equol is an active compound produced by intestinal bacteria through metabolizing soy isoflavones such as daidzein, and it exhibits multiple biological activities.
| Product name |
Equol |
Manufacture date |
Feb.22.2025 |
| Batch number |
SW250222 |
Analysis date |
Feb.23.2025 |
| Batch quantity |
500kg |
Expiry date |
Feb.22.2027 |
| Items |
Specifications |
Results |
| Description |
White Powder |
White Powder |
| Identification |
Positive |
Positive |
| Assay(by HPLC) |
98.0~102.0% |
99.64% |
| Absorbance(E1cm) |
465~495 |
482.5 |
| Melting Point |
189-190°C |
189-190°C |
| Loss On Drying |
0.5%max |
0.19% |
| Density |
1.286 g/cm3 |
1.286 g/cm3 |
| Residue On Ignition |
0.1%max |
0.03% |
| Related Substances |
Total:1.5%max |
<1.3% |
| |
Single:0.5%max |
<0.4% |
| Residue Solvents |
0.2%max |
0.10% |
| Heavy Metals |
20PPm max |
<10PPm |
| Conclusion |
Conform to Enterprise Standard |
| Packing description: |
Sealed export grade drum & double of sealed plastic bag |
| Storage: |
Store in cool & dry place not freeze, keep away from strong light and heat |
| Shelf life: |
2 years when properly stored |
1. Antineoplastic Effects
- Internal secretion-dependent neoplasms: Equol selectively binds to estrogen receptor beta (ERβ), inhibiting the proliferation of breast and prostate neoplastic cells. Clinical studies suggest that individuals capable of producing equol have a lower risk of breast and prostate neoplasms.
- Non-internal secretion-dependent neoplasms: In colorectal, gastric, and liver neoplasms, equol suppresses neoplastic growth through antioxidant, anti-inflammatory, and cell cycle regulatory mechanisms (e.g., modulating proteins like p21 and p27).
- Synergistic therapy: Equol enhances the efficacy of chemotherapy and may convert non-equol producers into producers by modulating gut microbiota, broadening its antineoplastic applications.
2. Antioxidant and Anti-inflammatory Effects
- Free radical scavenging: Equol's antioxidant capacity surpasses vitamins C and E, effectively neutralizing reactive oxygen species (ROS) and α-β unsaturated aldehydes, protecting cell membranes from oxidative damage.
- Regulation of signaling pathways: By activating ERβ-mediated ERK1/2 and nuclear factor-kappa B (NF-κB) pathways, equol upregulates antioxidant enzymes such as superoxide dismutase (SOD) and glutathione peroxidase, indirectly reducing oxidative stress.
- Anti-inflammatory mechanisms: Equol inhibits the release of inflammatory cytokines, alleviating vascular and tissue inflammation, particularly protecting against cardiovascular diseases like atherosclerosis.
3. Cardiovascular Protection
- Improved lipid metabolism: Equol reduces low-density lipoprotein cholesterol (LDL-C) and increases high-density lipoprotein cholesterol (HDL-C), lowering the risk of atherosclerosis.
- Vasodilation enhancement: It boosts NO production, improving endothelial function and reducing blood pressure.
- Antithrombotic effects: By mitigating oxidative vascular damage, equol decreases the incidence of cardiovascular events.
4. Hair and Skin Health
- Anti-hair loss and hair protection: Mimicking estrogen, equol improves postmenopausal hair thinning in women, enhancing hair density and shine while protecting against UV damage.
- Anti-aging and skin brightening: It inhibits skin oxidative stress and collagen degradation, reducing wrinkles, and blocks melanin production pathways to brighten skin tone. Equol also neutralizes free radicals from smoking, slowing skin aging.
5. Metabolic and Bone Health
- Improved bone density: In postmenopausal women, equol promotes osteoblast activity via estrogen-like effects, significantly increasing bone density and reducing osteoporosis risk.
- Glucose metabolism regulation: By activating the PKA signaling pathway in pancreatic β-cells, equol stimulates INS secretion, offering potential therapeutic benefits for type 2 diabetes.
6. Other Applications
- Ocular health: Equol enhances the transparency of cloudy eye lenses and is used to remedy age-related cataracts.
- Wound healing: As an olfactory nerve signaling molecule, it accelerates tissue repair post-surgery.
Key Considerations:
- Synergistic effects: Combining equol with vitamin E enhances antioxidant efficacy. In meat processing, it inhibits lipid oxidation and preserves color.
1. Customs clearance
a. By Express:
Normally there is no specical need for the recipient to clear the customs. If the customs has an objection, our rich experienced and professional group will help you clear the customs.
b. By Air and by Sea:
Our company will cooperate with the recipient to provide relevant file and information in the customs clearance procedure.
2. Payment
L/C, T/T, D/P, Western Union, Paypal, Money Gram, USDT, etc.
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