Sowu Supply Bile Salts CAS 16564-43-5 Sodium Glycochenodeoxycholate

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: SWP-BE175
• Certification: GMP, HSE, ISO 9001, USP, BP, SGS
• Suitable for: Adult
• State: Powder
• Purity: >98%
• Assay: 98%
• Appearance: White Powder
• OEM: Yes
• Certificate: GMP, Hse, ISO 9001, USP, Bp, SGS
• Test Method: HPLC
• Shelf Life: 2 Years
• Storage: Cool and Dry Place
• Sample: Yes
• MOQ: 1g
• Einecs: 1592732-453-0
• Melting Point: 160-170 °c
• Mf: C26h42nnao5
• Boiling Point: 655.6°c at 760 Mmhg
• CAS: 16564-43-5
• MW: 471.61
• Transport Package: Vacuum Sealed Foil Bag
• Specification: 1g/bag
• Trademark: Sowu
• Origin: China
• Production Capacity: 10kg/Month

Product Description

Product Description

Sodium glycochenodeoxycholate, a bile salt formed by the conjugation of deoxycholic acid and glycine in the liver, exhibits diverse biological activities and pharmaceutical applications. However, it is a relatively toxic bile salt, necessitating caution regarding its toxicity during use. In biological experiments, the active moiety of the compound remains identical between its salt and non-salt forms, but physical properties such as solubility may differ; selection should align with experimental requirements. Additionally, all related products are strictly intended for scientific research or pharmaceutical applications and must not be administered to humans.

Certifications

Product name	Sodium glycochenodeoxycholate	Manufacture date	Mar.15.2025
Batch number	SW250315	Analysis date	Mar.16.2025
Batch quantity	10kg	Expiry date	Mar.15.2027

   

Items	Specifications	Results
Appearance	White Crystalline powder	Conform
Assay	≥97%	99.46%
Moisture	≤5.0%	3.15%
Chloride	≤0.50%	0.3%
Residuue on Ignition	≤0.1%	0.05%
Heavy Metals	≤20ppm	Conform
Pb	≤5ppm	Conform
As	≤4ppm	Conform
Hg	≤0.3ppm	Conform
Cd	≤1.5ppm	Conform
Total Plate Count	≤100cfu/g	Conform
Yeasts and Molds	≤10cfu/g	Conform
E.coli	Negative	Negative
Conlusion	Conforming to Enterprise Standard

 

Packing description:	Sealed export grade drum & double of sealed plastic bag
Storage:	Store in cool & dry place not freeze, keep away from strong light and heat
Shelf life:	2 years when properly stored

Application

     1.Induction of Hepatocyte Apoptosis: Sodium glycochenodeoxycholate can dissolve lipids via its detergent-like effects and induce hepatocyte apoptosis. It inhibits lysosomal proteolysis, elevates lysosomal pH, suppresses autophagosome formation, and impairs lysosomal function in human normal hepatocytes, ultimately leading to apoptosis.
     2.Lipid Dissolution and Absorption: It exhibits detergent-like properties, enabling lipid dissolution and promoting fat absorption.
     3.Induction of Stem Cell-like Properties and Chemoresistance in Liver neoplasms Cells: Sodium glycochenodeoxycholate activates the STAT3 signaling pathway, thereby inducing stem cell-like characteristics and chemoresistance in hepatocellular carcinoma cells.
     4.Potential Therapeutic Applications: Owing to its bioactivity, Sodium glycochenodeoxycholate holds promise for research in cholestasis, liver neoplasms, and primary sclerosing cholangitis (PSC).

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a. By Express:
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