Sowu Supply Pharmaceutical Chemical CAS 129497-78-5 Verteporfin

• Customization: Available
• Powder: Yes
• Customized: Customized
• Model NO.: SWP-BE178
• Certification: GMP, HSE, ISO 9001, USP, BP, SGS
• Suitable for: Adult
• State: Powder
• Purity: >99%
• Assay: 99%
• Appearance: White Powder
• OEM: Yes
• Certificate: GMP, Hse, ISO 9001, USP, Bp, SGS
• Test Method: HPLC
• Shelf Life: 2 Years
• Storage: -20°c
• Sample: Yes
• MOQ: 1g
• Solubility: 2mg/Ml in DMSO
• COA: Yes
• Mf: 2c41h42n4o8
• Name: Verteporfin
• CAS: 129497-78-5
• MW: 1437.61
• Transport Package: Vacuum Sealed Foil Bag
• Specification: 1g/bag
• Trademark: Sowu
• Origin: China
• Production Capacity: 800kg/Month

Product Description

Product Description

Verteporfin is indicated for patients with subfoveal choroidal neovascularization (CNV) predominantly of the classic type, secondary to age-related macular degeneration, pathologic myopia, or suspected ocular histoplasmosis. For patients with subfoveal choroidal neovascularization predominantly of the occult type, there is insufficient evidence to support the use of verteporfin remedy.

Certifications

Product name	Verteporfin	Manufacture date	Mar.15.2025
Batch number	SW250315	Analysis date	Mar.16.2025
Batch quantity	800kg	Expiry date	Mar.15.2027

    

Packing description:	Sealed export grade drum & double of sealed plastic bag
Storage:	Store in cool & dry place not freeze, keep away from strong light and heat
Shelf life:	2 years when properly stored

Application

Verteporfin is activated by light to form cytotoxic products in an aerobic environment. During this process, the porphyrin transfers the absorbed energy to oxygen, forming a highly reactive and short-lived monooxygen. Single oxygen destroys various biological structures within its diffusion range. This process results in local vascular atresia, cell destruction, and, under certain circumstances, cell death. In plasma, verteporfin is mainly carried by low density lipoproteins (LDL). Photodynamic therapy (PDT) with verteporfin is selective.
On the one hand, it is the selection of the light irradiation site, on the other hand, the expression of LDL receptors in rapidly proliferating cells including choroidal neovascular endothelial cells is enhanced, so that rapidly proliferating cells can selectively and rapidly take up and accumulate verteporfin . The uptake of verteporfin by choroidal neovascularization is more rapid and selective than that of the retinal pigment epithelium, while other ocular structures contain less dr.u.g. Therefore, choroidal neovascularization can be selectively destroyed.

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